TOPIC DETAILS
Posted By : chanakya Posted On : Oct 10, 2017
Subject :mtDNA....
What is mtDNA? What is its relationship with the performance of a thoroughbred?

Will some one explain?
a
  ayyarnet said ... On : 10/12/2017 1:47:50 PM

Chanakya ji:

Mitochondria produce energy through a process called oxidative phosphorylation. This process uses oxygen and simple sugars to create adenosine triphosphate (ATP), the cell’s main energy source. As you are well aware that energy is necessary for running with good speed. Beyond this I am unable explain perhaps a good Veterinary Doctor with equine specialty may be able to assist you

Reference Website :https://ghr.nlm.nih.gov/primer/basics/mtdna

Mad Max:

Apology and I am very sorry I did not mention the Reference Site in my previous posting.

Thanks for correcting me.

Regards

ayyarnet

  manish said ... On : 10/12/2017 12:56:24 PM
@ Chanakya,

Seeing your track record, it seems to be a challenge

Yuo think that there is some knowledge which only you possess and nobody else.

But still million is far away...


  chanakya said ... On : 10/12/2017 10:26:40 AM
@ ayyarnet,

your posting about mtDNA is very correct but does not explicitly explain its relationship with performance in layman's term...

@ manish,


you may have to change your style, then only you may understand whether it isa query or a challenge...
you may take it anyway , you feel...

  Mad Max said ... On : 10/12/2017 8:36:19 AM
@ ayyarnet

Give courtesy to the website from which you copied the article:
https://ghr.nlm.nih.gov/primer/basics/mtdna


  VASUDEVAN said ... On : 10/11/2017 11:04:38 AM



a small circular DNA molecule found in the mitochondria of a cell. Mitochondrial DNA is inherited only from the mother.

  manish said ... On : 10/11/2017 10:47:47 AM
First please specify, whether its a genuine query or a challenge??

  ayyarnet said ... On : 10/11/2017 10:46:15 AM

Chanakya :

Eventhough performance depends on the quality of training and the current way of of breeding still the horse could have inherited certain qualities such as height and strength and id if any disease was therents with the parent animal that also could be passed on to the next generation.
Although most DNA is packaged in chromosomes within the nucleus, mitochondria also have a small amount of their own DNA. This genetic material is known as mitochondrial DNA or mtDNA.

Mitochondria are structures within cells that convert the energy from food into a form that cells can use. Each cell contains hundreds to thousands of mitochondria, which are located in the fluid that surrounds the nucleus (the cytoplasm).

Mitochondria produce energy through a process called oxidative phosphorylation. This process uses oxygen and simple sugars to create adenosine triphosphate (ATP), the cell’s main energy source. A set of enzyme complexes, designated as complexes I-V, carry out oxidative phosphorylation within mitochondria.

In addition to energy production, mitochondria play a role in several other cellular activities. For example, mitochondria help regulate the self-destruction of cells (apoptosis). They are also necessary for the production of substances such as cholesterol and heme (a component of hemoglobin, the molecule that carries oxygen in the blood).

Mitochondrial DNA contains 37 genes, all of which are essential for normal mitochondrial function. Thirteen of these genes provide instructions for making enzymes involved in oxidative phosphorylation. The remaining genes provide instructions for making molecules called transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), which are chemical cousins of DNA. These types of RNA help assemble protein building blocks (amino acids) into functioning proteins.



Best Regards
ayyarnet